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  1. Proteus mirabilis UreR coordinates cellular functions required for ...

    Mar 27, 2024 · In this study, we performed a comprehensive RNA-seq to define the P. mirabilis urea-induced transcriptome as well as the UreR regulon. We identified UreR as the first …

  2. Molecular Study of Urease ureR Gene of Proteus mirabilis Isolated …

    UreR, the transcriptional activator of the Proteus mirabilis urease gene cluster, is required for urease activity and virulence in experimental urinary tract infections.

  3. Urea-dependent Signal Transduction by the Virulence Regulator UreR

    Oct 4, 2002 · Urea freely diffuses into the bacterium Providencia stuartii and activates UreR, a member of the AraC family of transcriptional activators. Active UreR promotes transcription of …

  4. Transcriptional regulation of Proteus mirabilis urease by UreR

    These data suggest that induction by UreR, the protein that governs regulation of the urease operon, is exquisitely specific for urea and does not respond to closely related structural analogs.

  5. UreR, the Transcriptional Activator of the Proteus mirabilis Urease ...

    Proteus mirabilis, a cause of complicated urinary tract infection, produces urease, an essential virulence factor for this species. UreR, a member of the AraC/XylS family of transcriptional …

  6. Urea freely diffuses into the bacterium Providen-cia stuartii and activates UreR, a member of the AraC family of transcriptional activators. Active UreR pro-motes transcription of virulence …

  7. UreR, the transcriptional activator of the Proteus mirabilis …

    Proteus mirabilis, a cause of complicated urinary tract infection, produces urease, an essential virulence factor for this species. UreR, a member of the AraC/XylS family of transcriptional …

  8. UreR, the Transcriptional Activator of the - Infection and Immunity

    The plasmid-encoded urease gene cluster of the family Enterobacteriaceae is positively regulated by UreR, a member of the AraC family of transcriptional activators.

  9. New vectors for urea-inducible recombinant protein production

    Dec 25, 2022 · Induction is due to the activity of UreR, an AraC-family transcription factor, encoded by the ureR gene, located divergently upstream of ureD (Fig. 1). In the absence of …

  10. Identification of the Domains of UreR, an AraC-Like Transcriptional ...

    Proteus mirabilis urease catalyzes the hydrolysis of urea to CO2 and NH3, resulting in urinary stone formation in individuals with complicated urinary tract infections. UreR, a member of the …